Tottenham Hotspur secured a thrilling victory to climb into the Premier League's top four, courtesy of Son Heung-min's dramatic late winner against Luton.
Chelsea, however, faced frustration as they twice squandered leads against 10-man Burnley, settling for a 2-2 draw.
Meanwhile, Newcastle staged a remarkable comeback from 3-1 down to clinch a sensational 4-3 triumph over West Ham, while Fulham battled back for a 3-3 draw against bottom-placed Sheffield United.
Spurs, demonstrating their resilience, have now clinched victory from behind in four of their last five home games, showcasing their determination to secure a coveted return to the Champions League.
In a match filled with twists and turns, Tahith Chong stunned Tottenham with an early goal for Luton, only for a second-half resurgence led by Son and a crucial own goal from Issa Kabore to secure the win for the hosts.
Chelsea's Mauricio Pochettino faced criticism yet again as his side failed to capitalise on a numerical advantage against Burnley, with Vincent Kompany's dismissal adding to the drama. Despite Cole Palmer's penalty giving the Blues hope, Burnley's Josh Cullen and Dara O'Shea ensured a share of the spoils.
Newcastle's thrilling fightback saw them close the gap on West Ham, with Harvey Barnes emerging as the hero with two late strikes. However, their joy was tempered by Anthony Gordon's late sending-off.
Elsewhere, Everton's woes continued with a 2-1 defeat to Bournemouth, Nottingham Forest earned a valuable point against Crystal Palace, and Sheffield United were denied victory by Fulham's late resurgence.
As the race for the Champions League intensifies, Manchester United face a crucial clash with Brentford, while title contenders Liverpool, Manchester City, and Arsenal are set for decisive battles on Sunday.